Models used in "The Mutations in FGFR2 Associated Craniosynostoses are
Clustered in Five Structural Elements of Immunoglobulin-like Domain III of the Receptor"
by D.Steinberger, G.Vriend, J.Mulliken, U.Mueller
The subunit that was modelled to map all mutation information is the first one
outside the membrane. In these coordinate sets we have highly speculatively
put together all three subunits, and a highly speculative transmembrane helix.
We have no information regarding the presence or location of this transmembrane part,
and we have no information regarding the relative orientation of the three subunits; this
information is only provided to give you an idea about the relative size of things.
The lipids were 'borrowed' from the PDB file 2brd. Not that these lipids provide a
good membrane, but they do indicate roughly the dimensions of a membrane.
The only part of the model used in the article was the subunit facing the membrane.
get or view a model of the three subunits.
get or view the third (membrane facing) subunit.
You can also look at the postscript file model quality report
of the third subunit.