Alignments for "The Mutations in FGFR2 Associated Craniosynostoses are Clustered in Five Structural Elements of Immunoglobulin-like Domain III of the Receptor" by D.Steinberger, G.Vriend, J.Mulliken, U.Mueller

• rhe is template sequence
• ssr is secondary structure
• u 1 is subunit 1
• u 2 is subunit 2
• u 3 is subunit 3
• pb* are the corresponding strand indications found in Bork's landmark article

rhe                                         ESVLTQ-PPSASGTPGQRVTISCTGSATDIGSNSVIWYQQVPGKAPKLLIYYNDLLPSGVSDRFSASKSGTSASLAISGLESEDEADYYCAAWN--DSLDEPGFGGGTKLTVLGQPK
ssr                                           TT  - TSSSS TT  SSSSSS  TTTTTTT SSSSS  TTT  SSSS TTT   TT..TTSSSSSSTTSSSSSSTT  333 SSSSSSSSS--TTTTSSSS   SSSSS T
u 1                                         KYQISQ-PEVYVAAPGESLEVRCLLK--DA--AVISWTKD-----GVHLG---------PNNRTVLIG----EYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAI------
u 2                          DFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAG--GNPMPTMRWLKN--GKEFKQEH-----RIGGYKVRNQHW------SLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRP--
u 3                          NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY--SDAQPHIQWIKHVE-KNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQ--------
pb1                                                          bbbbbb          cccccc
pb1.....................                                                            bbbbbbbb   cccc                             fffffff
pb2                                                                         bbbbbbbb     cccc                                      fffffff
pb3                                                               bbbbbbbb     cccc                                         ffffffff