The hydrophobic ones are at the outside and the hydrophylic ones at the inside
and near the ends of the helices. If you let the students load the file
BRD_lip.pdb, they see some of the lipids. The lipids are not all around because
the molecule crystallized (in 2D crystals) as a trimer so you do'nt see lipids
at the trimer contact interfaces.
![]() |
One monomer from the Bacteriorhodopsin trimer with the lipids (that could be seen in the 2D electron diffraction reconstruction study) around it. |