Homology Modelling: Intro

After the Homology Modelling section you will:
Be able to perform homology modelling using web-based servers;
Understand the theoretical problems associated with Homology Modelling;
The homology modelling seminar;
The homology modelling article;

Homology Modelling is a technique to predict the structure of a protein from its sequence using the coordinates of a homologous protein with known structure.

We will explain homology modelling as an 8-step process. That is just a choice. Other people use three steps, very many steps, or even no steps at all.

It is nowadays sometimes also possible to predict the structure of a protein without the use of a homolog with know structure. This field is not yet developed far enough yet to teach about it because what we would teach today might be called old-stuff tomorrow.

Please be aware that about every step in Homology Modelling includes Force Field computations. We will mention a few of them, but later during the course -after the Force Field seminar- the Homology Modelling seminar will be quickly repeated with the inclusion of many of these Force fields.